House and Cuddy board a flight back to the United States from Singapore, where they were speakers at an international conference. Shortly after takeoff, a passenger seated next to House becomes violently ill. While House brushes it off as a hangover, Cuddy suspects the man might have a deadly contagious virus and the other passengers could be at risk. Assuming the worst, Cuddy suggests the plane turn back and land, but House dissuades the flight attendant and the flight continues on. As the man’s condition worsens, the rest of the passengers on the flight become increasingly uneasy, and so does House when a second passenger falls ill with the exact same rash and debilitating symptoms.
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