Well-known performance artist Afsoun Hamidi is admitted to the hospital, but when the team learns that her symptoms may have been self-inflicted as part of a documentary for her latest performance piece, they begin to question whether treatments are necessary and if they are unwittingly participating in the creation of a piece of her art. Meanwhile, a situation prompts House to do something very unexpected, a move that could change his relationship with Cuddy and Wilson permanently.

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